To maximize the effectiveness of our Ultimate Pimple & Blemish Patch, ensure you apply it to clean, dry skin, as using it on oily or damp skin can impair adhesion and reduce its healing benefits; choose the appropriate patch size to fully cover the blemish, as an ill-fitting patch may not deliver the full benefits of the potent anti-acne ingredients; gently press the patch onto the skin to ensure it adheres securely, as improper application can affect its ability to soothe and reduce redness; replace the patch daily or when it turns white to indicate that it has absorbed impurities and is no longer effective; and store the patches in a cool, dry place to maintain their potency and prevent contamination, ensuring they remain hypoallergenic and safe for all skin types.